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29-Aug-2017 11:26

After obtaining an informed consent, basic demographic details were collected, detailed history, and clinical examination was noted.Modified Rodnan skin score was calculated for all the patients.A detailed history, modified Rodnan score, clinical examination, routine investigation, antinuclear antibody, immuno biot, chest X-ray (CXR), pulmonary function test (PFT), and 6 min walk test (6MWT) were performed on all patients.High resolution computed tomography was done on those who consented.The baseline characteristics of the study subjects are tabulated in [Table 1].Common presenting complaints and their duration such as skin thickening, Raynaud's phenomenon, dyspnea, heart burn, and cough are also described in [Table 1].

Common presenting complaints were skin thickening in 98% and Raynaud's phenomenon in 98%.Using this criteria, 90% of the studied subjects had pulmonary involvement.Among 90 subjects with pulmonary involvement, all of them had skin thickening and Raynaud's phenomenon.Among 100 subjects, 87 underwent HRCT, basal sub pleural honey combing was the predominant finding in 32.1% followed by fibrosing alveolitis seen in 19.5% of subjects.

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Pulmonary involvement was defined as either radiological involvement (CXR/HRCT) or by Spirometry.Keywords: Diffusing capacity of the lungs for carbon monoxide (DLCO), forced expiratory volume at 1 s, forced vital capacity, metacarpo phalangeal, mixed connective tissue disorder, systemic sclerosis How to cite this URL: Deepa A S, Rachel RP, Ramchandran P, Devaraj U, Arnold S A, Shobha V, D'souza G.



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